Take the flow chart of the experimental plan that you have slaved over for your grant- and show it to a few people on your floor who are relatively unfamiliar with your work. Do this early in the grant writing process. If they can figure out where you are starting, how the experiments flow, and what you will have at the end, WITH A BARE MINIMUM OF VERBAL EXPLANATION FROM YOU, then you have a winner. If, however, they scratch their head in confusion at all those intersecting arrows and boxes- do not pass go, go directly back to the drawing board and start again. The key is to outline the experimental plan in a simple form, so the reviewers can take one look at it and see clearly where your work is going.
The last line is important for the entire grant. You always want the reviewers to understand and consider rather than decipher your proposal.
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